Some studies suggest a correlation between a history of head trauma and Alzheimer's disease. The correlation is not conclusive at this time.

Several studies have demonstrated a relationship between educational achievement and socioeconomic status in adult life and AD. It has been suggested that low education may be a surrogate marker for AD, perhaps by an association with malnutrition in childhood, infection and brain damage, or toxic exposures in early life.

Some other possible risk factors include exposure to heavy metals and female gender. Aluminum no longer is considered to play a role in the etiology of AD, although it is a neurotoxin. The patterns of impairment produced by aluminum exposure are not compatible with those seen in AD.