ANEMIA IN THE ELDERLY
| Clinical Overview | |
| Laboratory Parameters |
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Serum iron is the concentration of bound iron to transferrin, the iron transport protein. Usually transferrin is about one-third bound or saturated.
Serum iron levels may be decreased in iron-deficiency anemia or anemia or chronic disease. Iron-deficiency anemia may present with serum iron levels within normal range, resulting in a false negative.
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Therefore, serum iron levels alone are not adequate for diagnosis, and are best when interpreted with TIBC.
Serum iron levels are increased during hemolytic anemia and iron overload.